Large Language Models (LLMs) in Hypnosis, Leveraging Machine Learning to Map and Induce Hypnotic Trance States via Real-Time EEG, DORAs, VRH, HRV: Human-Led Hypnosis vs Algorithmically Hypnotherapy for Pain Management

Authors

  • Yash Srivastav D.K.R.R Pharmacy College, Amberpur, Sitapur (Uttar Pradesh), India Author
  • Raman Srivastava KP Singh Memorial Institute of Pharmacy, Sitapur, Lucknow, Uttar Pradesh, India Author
  • Stuti Verma Aryakul College of Pharmacy and Research, Sitapur, Uttar Pradesh, India Author
  • Anup Kumar Sirbaiya KP Singh Memorial Institute of Pharmacy, Sitapur, Lucknow, Uttar Pradesh, India Author
  • Shivani Singh D.K.R.R Pharmacy College, Amberpur, Sitapur (Uttar Pradesh), India Author
  • Kamini Prajapati D.K.R.R Pharmacy College, Amberpur, Sitapur (Uttar Pradesh), India Author
  • Vasu Tiwari KP Singh Memorial Institute of Pharmacy, Sitapur, Lucknow, Uttar Pradesh, India Author

DOI:

https://doi.org/10.64063/3049-1681.vol.3.issue6.2

Keywords:

Large Language Models, Hypnosis, EEG, HRV, Machine Learning, Pain Management, Neurofeedback, AI Hypnotherapy, VRH, Digital Therapeutics

Abstract

The investigation assessed the potential applications of LLMs, EEG neurofeedback, HRV analysis, DORAS systems, and VRH in the development of AI-powered hypnotherapy solutions for pain therapy. The results proved that AI-based hypnotherapy platforms had higher levels of customization, ability to monitor the states of trance, maintain consistency of sessions, and promote physiological adaptations compared to conventional hypnotherapy approaches based on human hypnotherapists. The quantitative analysis revealed that hypnotherapy sessions assisted by VRH delivered the most effective pain relief outcomes, whereas the EEG and HRV assessments revealed enhanced levels of autonomic relaxation and emotional control in the context of hypnotherapy. The researchers found that despite obvious strengths in terms of scalability, incorporation of neurofeedback, and responsiveness to individual conditions of patients, AI systems lack some qualities inherent to humans such as emotional empathy and rapport building. Overall, it can be concluded that future hypnotherapy systems are more likely to become hybrid human-AI solutions.

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Published

02-06-2026

How to Cite

Srivastav, Y. S., Srivastava, R. S., Verma, S. V., Sirbaiya, A. K. S., Singh, S. S., Prajapati, K. P., & Tiwari, V. T. (2026). Large Language Models (LLMs) in Hypnosis, Leveraging Machine Learning to Map and Induce Hypnotic Trance States via Real-Time EEG, DORAs, VRH, HRV: Human-Led Hypnosis vs Algorithmically Hypnotherapy for Pain Management. Journal of Pharmaceutical Research and Integrated Medical Sciences, 15-29. https://doi.org/10.64063/3049-1681.vol.3.issue6.2